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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T13524 9-cis-β-Carotene

Others Others
9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. It inhibits photoreceptor degeneration and restores retinal function in vivo.
T35983 Carotenoid Mixture

Carotenoid mixture is a mixture of carotenoids that contains the antioxidative and anti-inflammatory carotenoid capsanthin and the antioxidative vitamin A precursor β-carotene , as well as additional carotenoids and carotenoid esters.1,2,3,4 1.Kim, J.S., Lee, W.M., Rhee, H.C., et al.Red paprika (Capsicum annuum L.) and its main carotenoids, capsanthin and β-carotene, prevent hydrogen peroxide-induced inhibition of gap-junction intercellular communicationChem. Biol. Interact.254146-155(2016) 2.Na...
T35854 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)

9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.29(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-inducedGLUT4expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3Dietary administration of 9(Z)11(E)-co...

化合物

9-cis-β-Carotene
Cat.No: T13524
Synonym:
Target: Others
Carotenoid Mixture
Cat.No: T35983
Synonym:
Target:
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
Cat.No: T35854
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T1633 β-Carotene

beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素

Apoptosis; ROS; Endogenous Metabolite Apoptosis; Immunology/Inflammation; Metabolism
β-Carotene (Provitamin A) 是一种天然存在的视黄醇(维生素 A)前体。它是一种 ROS 调节剂,具有抗氧化和抗炎活性。它可作为抗氧化剂或者促氧化剂,可诱导乳腺癌细胞凋亡,具有抗癌活性。
T3138 Astaxanthin

β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin,虾青素

Reactive Oxygen Species; PPAR DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; NF-κB
Astaxanthin (trans-Astaxanthin) 是可从雨生红球藻等多种海洋生物中提取得到的红色类胡萝卜素,是过氧化物酶体增殖物活化受体γ 的调节剂,具有抗增殖、神经保护作用和抗炎活性。它是一种抗氧化剂,有用于癌症和心血管疾病的研究潜力,作为颜色添加剂用于动物食品中。
T7921 β-Cyclocitral

beta-Cyclocitral,β-环柠檬醛

Others Others
β-Cyclocitral 是 β-胡萝卜素的挥发性氧化衍生物,是微囊藻特有的掠食性动物防御信号。它是一种强大的驱虫剂。它是主要的挥发性萜类化合物之一,可以上调防御基因的表达,从而增强过量光照 (EL) 的适应性。
T2723 Ketoisophorone

茶香酮,4-Oxoisophorone,2,6,6-Trimethyl-2-cyclohexene-1,4-dione

Others Others
Ketoisophorone (2,6,6-Trimethyl-2-cyclohexene-1,4-dione) 是工业上重要的环状内酯,是合成类胡萝卜素和调味剂的关键中间体。
T11041 Dihydro-β-erythroidine hydrobromide

DHβE hydrobromide

Others Others
Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs). Dihydro-β-carotene hydrobromide showed selectivity to α4β4 and α4β2nAChR, with IC50 of 0.19 and 0.37 μM,
T19169 9-cis-Retinal

Others Others
9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to CRBP-I and CRBP-II (Kds: 8 nM and 5 nM). It expedites differentiation and maturation of rod photoreceptors in r

天然产物

β-Carotene
Cat.No: T1633
Synonym: beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素
Target: Apoptosis, ROS, Endogenous Metabolite
Astaxanthin
Cat.No: T3138
Synonym: β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin,虾青素
Target: Reactive Oxygen Species, PPAR
β-Cyclocitral
Cat.No: T7921
Synonym: beta-Cyclocitral,β-环柠檬醛
Target: Others
Ketoisophorone
Cat.No: T2723
Synonym: 茶香酮,4-Oxoisophorone,2,6,6-Trimethyl-2-cyclohexene-1,4-dione
Target: Others
Dihydro-β-erythroidine hydrobromide
Cat.No: T11041
Synonym: DHβE hydrobromide
Target: Others
9-cis-Retinal
Cat.No: T19169
Synonym:
Target: Others
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